2022 Indianapolis Colts Schedule
| Pre Season |
|---|
| Opponent |
| @ BUF |
| DET |
| TB |
| Reg. Season |
| Opponent |
| @ HOU |
| @ JAC |
| KC |
| TEN |
| @ DEN |
| JAC |
| @ TEN |
| WAS |
| @ NE |
| @ LV |
| PHI |
| PIT |
| @ DAL |
| BYE WEEK |
| @ MIN |
| LAC |
| @ NYG |
| HOU |
| - | ||||||
|---|---|---|---|---|---|---|
| Date | Status | Record | Spread | O/U | Tickets | Network |
| 08/13 | 24 - 27 L | 0-1-0 | - | - | NFL Network | |
| 08/20 | 27 - 26 L | 0-2-0 | - | - | ||
| 08/27 | 10 - 27 W | 1-2-0 | - | - | ||
| - | ||||||
| Date | Status | Record | Spread | O/U | Tickets | Network |
| 09/11 Wk 1 | 20 - 20 Tie | 1-2-1 | - | - | CBS | |
| 09/18 Wk 2 | 0 - 24 L | 1-3-1 | - | - | CBS | |
| 09/25 Wk 3 | 17 - 20 W | 2-3-1 | - | - | CBS | |
| 10/02 Wk 4 | 24 - 17 L | 2-4-1 | - | - | FOX | |
| 10/06 Wk 5 | 12 - 9 W | 3-4-1 | - | - | Amazon Prime Video | |
| 10/16 Wk 6 | 27 - 34 W | 4-4-1 | - | - | CBS | |
| 10/23 Wk 7 | 10 - 19 L | 4-5-1 | - | - | CBS | |
| 10/30 Wk 8 | 17 - 16 L | 4-6-1 | - | - | FOX | |
| 11/06 Wk 9 | 3 - 26 L | 4-7-1 | - | - | CBS | |
| 11/13 Wk 10 | 25 - 20 W | 5-7-1 | - | - | CBS | |
| 11/20 Wk 11 | 17 - 16 L | 5-8-1 | - | - | CBS | |
| 11/28 Wk 12 | 24 - 17 L | 5-9-1 | - | - | ESPN Deportes | |
| 12/04 Wk 13 | 19 - 54 L | 5-10-1 | - | - | NBC | |
| - | - | - | - | - | - | - |
| 12/17 Wk 15 | 36 - 39 L | 5-11-1 | - | - | NFL Network | |
| 12/26 Wk 16 | 20 - 3 L | 5-12-1 | - | - | ESPN Deportes | |
| 01/01 Wk 17 | 10 - 38 L | 5-13-1 | - | - | CBS | |
| 01/08 Wk 18 | 32 - 31 L | 5-14-1 | - | - | CBS | |